替米利芬

• 常用名: 替米利芬
• 英文名: Tesmilifene
• CAS号: 98774-23-3
• 分子量: 283.408
• 密度: 1.0±0.1 g/cm3
• 沸点: 397.0±30.0 °C at 760 mmHg
• 分子式: C₁₉H₂₅NO
• 熔点: N/A
• 闪点: 116.8±26.9 °C

替米利芬用途

Tesmilifene is a novel agent that augments cytotoxicity of various chemotherapeutic agents both in vitro and in vivo. It binds selectively to the high-affinity microsomal antiestrogen binding site (Ki=50nm) but has no affinity for estrogen receptors. Inhi

替米利芬名称

• 中文名: 替米利芬
• 英文名: Tesmilifene
• 中文别名: 帕托珠利 | N,N-二乙基-2-(4-苄基苯氧基)乙胺

替米利芬物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 397.0±30.0 °C at 760 mmHg
• 分子式: C₁₉H₂₅NO
• 分子量: 283.408
• 闪点: 116.8±26.9 °C
• 精确质量: 283.193604
• PSA: 12.47000
• LogP: 5.04
• InChIKey: NFIXBCVWIPOYCD-UHFFFAOYSA-N
• SMILES: CCN(CC)CCOc1ccc(Cc2ccccc2)cc1
• 外观性状: 透明,无色液体
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.543

替米利芬靶点实验

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实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_OPM1-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-OC1MY5-m4-1

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-KMS_34-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_L363-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_OCIMY7-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-MM1R-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-mm1s-m4-1

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替米利芬英文别名

• DPPE
• UNII-I43T3ID6G2
• (2-(4-benzylphenoxy)ethyl)diethylamine
• tesmilifene
• 2-(4-Benzylphenoxy)-N,N-diethylethanamine
• 2-[(a-Phenyl-p-tolyl)oxy]triethylamine
• Depmpe