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N-(对甲酰基肉桂酰)邻氨基苯甲酸

更新时间:2025-09-22 17:51:47

N-(对甲酰基肉桂酰)邻氨基苯甲酸结构式
N-(对甲酰基肉桂酰)邻氨基苯甲酸结构式
品牌特惠专场
常用名 N-(对甲酰基肉桂酰)邻氨基苯甲酸 英文名 N-(P-Amylcinnamoyl)Anthranilic Acid
CAS号 99196-74-4 分子量 337.41200
密度 1.178±0.06 g/cm3 (20 °C, 760 mmHg) 沸点 563.1±50.0 °C (760 mmHg)
分子式 C21H23NO3 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS09
GHS09
信号词 Warning

 N-(对甲酰基肉桂酰)邻氨基苯甲酸用途


氨基苯甲酸 (ACA) 是一种广谱磷脂酶 A2 抑制剂,可阻断瞬时受体电位 (TRP) 通道。抑制心室肌细胞中钙激活的氯化物电流。ACA 调节多种离子通道。

 N-(对甲酰基肉桂酰)邻氨基苯甲酸名称

中文名 N-(对甲酰基肉桂酰)邻氨基苯甲酸
英文名 Benzoic acid, 2-[[(2E)-1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]
英文别名 更多

 N-(对甲酰基肉桂酰)邻氨基苯甲酸物理化学性质

密度 1.178±0.06 g/cm3 (20 °C, 760 mmHg)
沸点 563.1±50.0 °C (760 mmHg)
分子式 C21H23NO3
分子量 337.41200
精确质量 337.16800
PSA 66.40000
LogP 4.84240
InChIKey GAMRBCZMOOMBSQ-CCEZHUSRSA-N
SMILES CCCCCc1ccc(C=CC(=O)Nc2ccccc2C(=O)O)cc1
外观性状 固体
储存条件 室温

 N-(对甲酰基肉桂酰)邻氨基苯甲酸安全信息

符号 GHS09
GHS09
信号词 Warning
危害声明 H410
警示性声明 P273-P501
危害码 (欧洲) N
危险品运输编码 UN 3077 9 / PGIII

 N-(对甲酰基肉桂酰)邻氨基苯甲酸文献8

更多文献
Des-Arg9-bradykinin causes kinin B1 receptor mediated endothelium-independent contractions in endotoxin-treated porcine coronary arteries.

Pharmacol. Res. 90 , 18-24, (2014)

This study examined responses of isolated pig coronary arteries after kinin B1 receptor induction by endotoxin. Des-Arg9-bradykinin (DBK) induced concentration-dependent, endothelium-independent contr...

Enhanced cytotoxicity in triple-negative and estrogen receptor‑positive breast adenocarcinoma cells due to inhibition of the transient receptor potential melastatin-2 channel.

Oncol. Rep. 34 , 1589-98, (2015)

We previously demonstrated a unique protective role for the transient receptor potential, melastatin-2 (TRPM2) cation channel in breast cancer cells. In the present study, we investigated the chemothe...

Diglycolic acid is the nephrotoxic metabolite in diethylene glycol poisoning inducing necrosis in human proximal tubule cells in vitro.

Toxicol. Sci. 124 , 35-44, (2011)

Diethylene glycol (DEG), a solvent and chemical intermediate, can produce an acute toxic syndrome, the hallmark of which is acute renal failure due to cortical tubular degeneration and proximal tubula...

 N-(对甲酰基肉桂酰)邻氨基苯甲酸靶点实验

查看更多实验

实验名称:Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-ind...
来源:ChEMBL
靶标:Transient receptor potential cation channel subfamily M member 2
External Id:CHEMBL4154411
实验名称:Inhibition of PLA2 (unknown origin) using soybean phosphatidylcholine as substrate at...
来源:ChEMBL
靶标:Phospholipase A2
External Id:CHEMBL4835360
实验名称:Human TRPC3 (Transient Receptor Potential channels)
来源:IUPHAR-DB
靶标:TRPC3 (Transient Receptor Potential channels) [Homo sapiens]
External Id:488_Human
实验名称:Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-ind...
来源:ChEMBL
靶标:Transient receptor potential cation channel subfamily M member 2
External Id:CHEMBL4154412
实验名称:Agonist activity at human TRPA1 Phe909Ala mutant expressed in HEK293 cells assessed a...
来源:ChEMBL
靶标:Transient receptor potential cation channel subfamily A member 1
External Id:CHEMBL4347317
实验名称:Inhibition of human TRPM8 expressed in HEK293T cells assessed as blocked of menthol-a...
来源:ChEMBL
靶标:Transient receptor potential cation channel subfamily M member 8
External Id:CHEMBL4835357
实验名称:Agonist activity at human TRPA1 Phe909Ala mutant expressed in HEK293 cells assessed a...
来源:ChEMBL
靶标:Transient receptor potential cation channel subfamily A member 1
External Id:CHEMBL4347316
实验名称:Inhibition of PLA2 (unknown origin) using soybean phosphatidylcholine as substrate at...
来源:ChEMBL
靶标:Phospholipase A2
External Id:CHEMBL4835362
实验名称:Inhibition of human TRPM2 expressed in HEK293T cells cotransfected with GFP assessed ...
来源:ChEMBL
靶标:Transient receptor potential cation channel subfamily M member 2
External Id:CHEMBL4844234
实验名称:Human TRPC6 (Transient Receptor Potential channels)
来源:IUPHAR-DB
靶标:TRPC6 (Transient Receptor Potential channels) [Homo sapiens]
External Id:491_Human
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 N-(对甲酰基肉桂酰)邻氨基苯甲酸英文别名

BML 264
N-(P-AMYLCINNAMOYL)ANTHRANILIC ACID
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