6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮

更新时间：2025-09-01 09:11:49

6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮结构式	常用名	6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮	英文名	6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
	CAS号	99471-41-7	分子量	224.25800
	密度	N/A	沸点	N/A
	分子式	C₁₄H₁₂N₂O	熔点	N/A
	MSDS	N/A	闪点	N/A

中文名	6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮
英文名	6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
英文别名	更多

分子式	C₁₄H₁₂N₂O
分子量	224.25800
精确质量	224.09500
PSA	45.48000
LogP	2.71840
InChIKey	MPGBYGNPFRLHAO-UHFFFAOYSA-N
SMILES	O=C1CCc2cc(-c3cccnc3)ccc2N1

6-溴-1,2,3,4-四氢-2-喹啉酮

3279-90-1

二乙基(3-吡啶基)硼烷

89878-14-8

~69%

6-(吡啶-3-基)-3,4-...

99471-41-7

文献：Martinez; Walker; Hirschfeld; Bruno; Yang; Maloney Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 620 - 628

3,4-二氢-2(1H)-喹啉酮

553-03-7

6-(吡啶-3-基)-3,4-...

99471-41-7

文献：Martinez; Walker; Hirschfeld; Bruno; Yang; Maloney Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 620 - 628

2,4,6-三溴苯胺

74497-02-2

6-(吡啶-3-基)-3,4-...

99471-41-7

文献：MERCK SHARP and DOHME CORP.; ElexoPharm GmbH; HOYT, Scott, B.; PETRILLI, Whitney Lane; LONDON, Clare; XIONG, Yusheng; TAYLOR, Jerry Andrew; ALI, Amjad; LO, Michael; HENDERSON, Timothy, J.; HU, Qingzhong; HARTMANN, Rolf; YIN, Lina; HEIM, Ralf; BEY, Emmanuel; SAXENA, Rohit; SAMANTA, Swapan Kumar; KULKARNI, Bheemashankar, A. Patent: WO2012/148808 A1, 2012 ; WO 2012/148808 A1

6-溴-1,2,3,4-四氢-2-喹啉酮

3279-90-1

吡啶-3-硼酸

1692-25-7

~94%

6-(吡啶-3-基)-3,4-...

99471-41-7

文献：Universitat des Saarlandes Patent: US2011/112067 A1, 2011 ; Location in patent: Page/Page column 34; 35 ; US 20110112067 A1

3-氯-N-苯基丙酰胺

3460-04-6

6-(吡啶-3-基)-3,4-...

99471-41-7

3-溴吡啶

626-55-1

6-溴-1,2,3,4-四氢-2-喹啉酮

3279-90-1

6-(吡啶-3-基)-3,4-...

99471-41-7

文献：Alabaster; Bell; Campbell; Ellis; Henderson; Roberts; Ruddock; Samuels; Stefaniak Journal of Medicinal Chemistry, 1988 , vol. 31, # 10 p. 2048 - 2056

6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮上游产品 6
CAS号3279-90-1 6-溴-1,2,3,4-四氢-2-喹啉酮 CAS号1692-25-7 吡啶-3-硼酸 CAS号89878-14-8 二乙基(3-吡啶基)硼烷 CAS号553-03-7 3,4-二氢-2(1H)-喹啉酮
CAS号3460-04-6 3-氯-N-苯基丙酰胺 CAS号626-55-1 3-溴吡啶
6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮下游产品 0

实验名称：Inhibition of human CYP11B2 expressed in hamster V79 MZh cells assessed as conversion...
来源：ChEMBL
靶标：Cytochrome P450 11B2, mitochondrial
External Id：CHEMBL1768362

实验名称：Percentage increase in dP/dt maximum observed with 4-[4-[2-(1,1-dioxo-2-isothiazolidi...
来源：ChEMBL
靶标：Canis lupus familiaris
External Id：CHEMBL667664

实验名称：Intrinsic activity calculated as the ratio of the maximum response to the compound to...
来源：ChEMBL
靶标：Cavia porcellus
External Id：CHEMBL687848

实验名称：Inhibition of human CYP11B2 expressed in hamster V79 MZh cells
来源：ChEMBL
靶标：Cytochrome P450 11B2, mitochondrial
External Id：CHEMBL989835

实验名称：Inhibition of human CYP11B2 expressed in hamster V79 MZh cells at 500 nM
来源：ChEMBL
靶标：Cytochrome P450 11B2, mitochondrial
External Id：CHEMBL989834

实验名称：Selectivity ratio, IC50 for human CYP11B1 to IC50 for human CYP11B2
来源：ChEMBL
靶标：N/A
External Id：CHEMBL989837

实验名称：Inhibition of human CYP11B1 expressed in hamster V79 MZh cells
来源：ChEMBL
靶标：Cytochrome P450 11B1, mitochondrial
External Id：CHEMBL989836

实验名称：Protection against mortality in pulmonary thromboembolism model in mice at 10 mg/kg
来源：ChEMBL
靶标：Mus musculus
External Id：CHEMBL729595

实验名称：Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect micro...
来源：ChEMBL
靶标：Cytochrome P450 1A2
External Id：CHEMBL989843

实验名称：Protection against mortality in pulmonary thromboembolism model in mice at 1 mg/kg
来源：ChEMBL
靶标：Mus musculus
External Id：CHEMBL728712

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6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-one

6-(pyridin-3-yl)-3,4-dihydrocarbostyril

6-(3-pyridyl)-3,4-dihydrocarbostyril

6-Pyridin-3-yl-3,4-dihydroquinolin-2(1H)-on

2(1H)-Quinolinone,3,4-dihydro-6-(3-pyridinyl)

6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮

6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮名称

6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮物理化学性质

6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮合成线路

6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮上下游产品

6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮靶点实验

6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮英文别名

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