Tetrahedron letters

PCP-Bis (phosphinite) pincer complexes: new homogeneous catalysts for α-arylation of ketones

F Churruca, R SanMartin, I Tellitu, E Domínguez

Index: Churruca, Fatima; SanMartin, Raul; Tellitu, Imanol; Dominguez, Esther Tetrahedron Letters, 2006 , vol. 47, # 19 p. 3233 - 3237

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Citation Number: 42

Abstract

Two new p-alkoxycarbonylated palladium bis (phosphinite) PCP pincer complexes are easily prepared and for the first time evaluated as homogeneous catalysts in α-arylation of ketone enolates. Apart from the total absence of phenyl–aryl exchange by-products and significantly low catalyst loadings, the general α-arylation protocols described in this letter feature not only a broad applicability to a range of ketones and aryl bromides with marked ...