Hydrosilanes Are Not Always Reducing Agents for Carbonyl Compounds, II: Ruthenium??Catalyzed Deprotection of tert??Butyl Groups in Carbamates, Carbonates, …

…, H Kuroiwa, Y Motoyama, H Nagashima

Index: Hanada, Shiori; Yuasa, Akihiro; Kuroiwa, Hirotaka; Motoyama, Yukihiro; Nagashima, Hideo European Journal of Organic Chemistry, 2010 , # 6 p. 1021 - 1025

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Citation Number: 10

Abstract

Abstract Hydrosilanes act as a reagent to cleave the C–O bond of OtBu groups in carbamates, carbonates, esters, and ethers by catalysis of a triruthenium cluster. The reaction offers a novel deprotection method for OtBu groups under neutral conditions, showing unique selectivities that have never been accomplished with conventional Brønsted or Lewis acidic promoters. Possible mechanisms for C–O cleavage are discussed on the ...