Tetrahedron letters

Anti-AIDS agents 83. Efficient microwave-assisted one-pot preparation of angular 2, 2-dimethyl-2H-chromone containing compounds

T Zhou, Q Shi, KH Lee

Index: Zhou, Ting; Shi, Qian; Lee, Kuo Hsing Tetrahedron Letters, 2010 , vol. 51, # 33 p. 4382 - 4386

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Citation Number: 20

Abstract

A novel and efficient microwave-assisted one-pot reaction was developed to synthesize angular 2, 2-dimethyl-2H-chromone-containing compounds, which is the first and key step in the synthesis of potent DCK and DCP anti-HIV agents. The newly developed microwave synthesis conditions dramatically shortened the reaction time from 2days to 4h with improved yields.