Kinetic stability of novel nitrile ylides

…, SJ Eustace, NM Tynan, NN Pham-Tran…

Index: Hegarty, Anthony F.; Eustace, Stephen J.; Tynan, Nuala M.; Pham-Tran, Nguyen-Nguyen; Nguyen, Minh Tho Journal of the Chemical Society. Perkin Transactions 2, 2001 , # 7 p. 1239 - 1246

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Abstract

A series of relatively stable novel trifluoromethyl substituted nitrile ylides have been generated by base promoted elimination of hydrogen chloride from the corresponding imidoyl chlorides in acetonitrile and aqueous dioxane solution at 25° C. The formation and decay of these sometimes highly coloured species was monitored spectrophotometrically. The rates of formation were first order in base, and the subsequent reaction with solvent ...