Acylation reactions mediated by tantalum carboxylates

K Joshi, J Bao, AS Goldman, J Kohn

Index: Joshi, Kiran; Bao, Jiang; Goldman, Alan S.; Kohn, Joachim Journal of the American Chemical Society, 1992 , vol. 114, # 17 p. 6649 - 6652

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Citation Number: 17

Abstract

Abstract: Facile nucleophilic attack on coordinated carboxylate ligands is reported: complexes of tantalum (V) react rapidly with amines and amino acid esters to give the corresponding amides. Cyclopentadienyltantalum (V) amino acid carboxylate complexes have been prepared and reacted with free amino acid esters to give dipeptides in good yield and with high stereochemical purity.