Chemistry–A European Journal

Microwave??Assisted, Aqueous Wittig Reactions: Organic??Solvent??and Protecting??Group??Free Chemoselective Synthesis of Functionalized Alkenes

J McNulty, P Das, D McLeod

Index: McNulty, James; Das, Priyabrata; McLeod, David Chemistry - A European Journal, 2010 , vol. 16, # 23 p. 6756 - 6760

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Citation Number: 58

Abstract

The Wittig olefination reaction [1] is regarded as one of the most strategic, widely applicable carbon–carbon doublebond-forming processes available in organic synthesis.[2–4] The reaction has had an enormous impact on the sophistication of the total synthesis of organic molecules.[5] Some drawbacks of the reaction are the lack of stereocontrol achieved in certain cases, for example, in the synthesis of stilbenes from semistabilised ylides,[6] and ...