Matthew D. Cliff and Stephen G. me * ... Departm.ent of Chemistry, University of Wollongong, Wollongong, New South Wales 2522, Australia ... A method for preparing trihydroxybutyl analogues of the biologically active compound 2-acetyl- 4(5)-(1,2,3,4-tetrahydroxybutyl)imidazole (THI) is reported. "his method employs a palladium(0)- catalyzed coupling of l-(ethoxymethyl)-4-iodoimidazole (3a) to functionalized vinylstannane 11, ...
