Enantiodivergent chemoenzymatic synthesis of (R)-and (S)-β-proline in high optical purity

…, J Lebreton, V Alphand, R Furstoss

Index: Mazzini; Lebreton; Alphand; Furstoss Journal of Organic Chemistry, 1997 , vol. 62, # 15 p. 5215 - 5218

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Citation Number: 63

Abstract

A number of studies were recently directed toward elaboration of new synthetic approaches to the enantiomerically pure forms of nonproteinogenic amino acids. 1 For instance, peptide structures involving the pyrrolidine moiety have received considerable attention over the past few years, 2 and recent reports have focused on the use of such pyrrolidine analogues to prepare biologically active compounds. 2, 3