Tetrahedron letters

Asymmetric reduction of oxime ethers. Distinction of anti and syn isomers leading to enantiomeric amines.

Y Sakito, Y Yoneyoshi, G Suzukamo

Index: Sakito, Yoji; Yoneyoshi, Yukio; Suzukamo, Gohfu Tetrahedron Letters, 1988 , vol. 29, # 2 p. 223 - 224

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Citation Number: 60

Abstract

Abstract Anti and syn ketoxime ethers were reduced with a chiral reducing agent prepared from (−)-norephedrine and 2 eq of BH 3 to give S and R amines respectively in up to 92% ee. The preferred absolute configuration of the amine was depended on the geometry of ...