(-)-norephedrine
(-)-norephedrine structure
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Common Name | (-)-norephedrine | ||
|---|---|---|---|---|
| CAS Number | 492-41-1 | Molecular Weight | 151.206 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 288.1±20.0 °C at 760 mmHg | |
| Molecular Formula | C9H13NO | Melting Point | 51-53 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 128.1±21.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Summary: Norephedrine, also known as (1R,2S)-2-amino-1-phenylpropan-1-ol, has a CAS number of 492-41-1. Its molecular formula is C9H13NO, with a molecular weight of 151.206. The熔点is 51-53°C, and the沸点is 288.1±20.0°C. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | (1R,2S)-2-amino-1-phenylpropan-1-ol |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 288.1±20.0 °C at 760 mmHg |
| Melting Point | 51-53 °C(lit.) |
| Molecular Formula | C9H13NO |
| Molecular Weight | 151.206 |
| Flash Point | 128.1±21.8 °C |
| Exact Mass | 151.099716 |
| PSA | 46.25000 |
| LogP | 0.81 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.558 |
| InChIKey | DLNKOYKMWOXYQA-CBAPKCEASA-N |
| SMILES | CC(N)C(O)c1ccccc1 |
| Storage condition | 2-8°C |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | RC2275000 |
| HS Code | 2939440000 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 10 | |
![(1R,2S)-1-phenyl-2-[((1R)-phenylethyl)amino]-1-propanol Structure](https://image.chemsrc.com/caspic/328/154170-05-5.png)
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CAS#:299-42-3![PROPIONIC ACID (1R,2S)-2-[N-BENZYL-N-(MESITYLENESULFONYL)AMINO]-1-PHENYLPROPYL ESTER structure](https://image.chemsrc.com/caspic/096/187324-66-9.png)
CAS#:187324-66-9This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2939440000 |
|---|
This table lists relevant public references with title, journal and publication metadata for this compound.
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental... |
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Forensic analysis of hallucinogenic mushrooms and khat (Catha edulis Forsk) using cation-exchange liquid chromatography.
Forensic Sci. Int. 195(1-3) , 160-4, (2010) Hallucinogenic mushrooms (e.g. Psilocybe and Panaeolus species) as well as leaves and young shoots of the khat tree (Catha edulis Forsk) are illicit drugs in many countries. The exact concentration of... |
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Keep an eye on the pupil: developing countries under chemical attack.
Intern. Emerg. Med. 4(3) , 231-3, (2009)
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This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Dose corresponding to a 5 mmHg increase in Intraurethral pressure (IUP) was determine...
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL648635
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Name: In vitro percent efficacy of compound was tested in rabbit urethra
Source: ChEMBL
Target: Oryctolagus cuniculus
External Id: CHEMBL766564
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Name: Affinity against 5-hydroxytryptamine receptors in rat fundus model
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 3B
External Id: CHEMBL619177
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Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
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Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
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Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
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Name: Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimo...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 1B3
External Id: CHEMBL3039491
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Name: Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H...
Source: Southern Research Institute
Target: CFTR
External Id: CF Folding
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Name: The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre...
Source: 11924
Target: N/A
External Id: CGM data for Cell Systems paper Dec 2015
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Name: Increase the activity of the Burkholderia fixLJ 2-component system
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Burkholderia multivorans
External Id: HMS1625
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (-)-Norephedrin |
| MFCD00066044 |
| (1S,2R)-H2NCH(Me)CH(OH)Ph |
| l-Norephedrine |
| (-)-Phenylpropanolamine |
| (-)-erythro-2-Amino-2-methyl-1-phenylethanol |
| (1R,2S)-2-amino-1-phenyl-propan-1-ol |
| (1R,2S)-(-)-norephedrine |
| (1R,2S)-2-Amino-1-phenyl-1-propanol |
| (aR)-a-[(1S)-1-Aminoethyl]benzenemethanol |
| USAF CS-6 |
| l-Phenylpropanolamine |
| L-ERYTHRO-(1R,2S)-2-AMINO-1-PHENYLPROPAN-1-OL |
| Mydriatin |
| EINECS 207-755-7 |
| (R,S)-(-)-Norephedrine |
| (-)-norephedrine |
| (1R,2S)-2-amino-1-phenylpropan-1-ol |
| [R-(R*,S*)]-a-(1-Aminoethyl)benzenemethanol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the downstream products of (1R,2S)-2-amino-1-phenylpropan-1-ol? |
| A: Related downstream products(CAS) of (1R,2S)-2-amino-1-phenylpropan-1-ol: 3198-15-0;492-39-7;4187-57-9;34566-04-6;187324-63-6;30275-30-0;937-52-0;30339-30-1;299-42-3;187324-66-9. |
| Q: What is the melting point of (1R,2S)-2-amino-1-phenylpropan-1-ol? |
| A: Melting point of (1R,2S)-2-amino-1-phenylpropan-1-ol is 51-53 °C(lit.). |
| Q: What are the storage conditions for (1R,2S)-2-amino-1-phenylpropan-1-ol? |
| A: Storage conditions for (1R,2S)-2-amino-1-phenylpropan-1-ol: 2-8°C. |
| Q: What is the polar surface area (PSA) of (1R,2S)-2-amino-1-phenylpropan-1-ol? |
| A: Polar surface area (PSA) of (1R,2S)-2-amino-1-phenylpropan-1-ol is 46.25000. |
| Q: What is the molecular weight of (1R,2S)-2-amino-1-phenylpropan-1-ol? |
| A: Molecular weight of (1R,2S)-2-amino-1-phenylpropan-1-ol is 151.206. |
| Q: What is the LogP of (1R,2S)-2-amino-1-phenylpropan-1-ol? |
| A: LogP of (1R,2S)-2-amino-1-phenylpropan-1-ol is 0.81. |
| Q: What is the InChIKey of (1R,2S)-2-amino-1-phenylpropan-1-ol? |
| A: InChIKey of (1R,2S)-2-amino-1-phenylpropan-1-ol is DLNKOYKMWOXYQA-CBAPKCEASA-N. |
| Q: What is the boiling point of (1R,2S)-2-amino-1-phenylpropan-1-ol? |
| A: Boiling point of (1R,2S)-2-amino-1-phenylpropan-1-ol is 288.1±20.0 °C at 760 mmHg. |
| Q: What is the molecular formula of (1R,2S)-2-amino-1-phenylpropan-1-ol? |
| A: Molecular formula of (1R,2S)-2-amino-1-phenylpropan-1-ol is C9H13NO. |
| Q: What is the safety information for (1R,2S)-2-amino-1-phenylpropan-1-ol? |
| A: Safety information for (1R,2S)-2-amino-1-phenylpropan-1-ol: S26. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Henan Tianfu Chemical Co., Ltd. |