Chirality

Solution??phase synthesis and evaluation of tetraproline chiral stationary phases

Z Dai, G Ye, CU Pittman, T Li

Index: Dai, Zhi; Ye, Guozhong; Pittman Jr., Charles U.; Li, Tingyu Chirality, 2012 , vol. 24, # 4 p. 329 - 338

Full Text: HTML

Citation Number: 4

Abstract

Abstract A protocol was developed for the solution-phase synthesis of multigram amounts of two 9-fluorenylmethoxycarbonyl (Fmoc)-protected tetraproline peptides. These tetraproline peptides were then attached to amino derivatized silica gel. The replacement of the Fmoc group with the trimethylacetyl group lead to two tetraproline chiral stationary phases (CSPs). A comparison of the chromatographic behavior of these two solution-phase-synthesized ...

 Related Synthetic Route
(S)-(+)-1,2-DIPHENYLETHANOL Structure

5773-56-8

(S)-(+)-1,2-DIP...

~%

(R)-(-)-1,2-Diphenylethanol Structure

41822-67-7

(R)-(-)-1,2-Dip...

(S)-1,2-diphenylethanol Structure

63180-94-9

(S)-1,2-dipheny...

Fmoc-Pro-Pro-O-t-butyl ester Structure

1366733-84-7

Fmoc-Pro-Pro-O-...

~98%

Fmoc-Pro-Pro-OH Structure

129223-22-9

Fmoc-Pro-Pro-OH

Fmoc-Pro-O-t-Bu Structure

129472-19-1

Fmoc-Pro-O-t-Bu

~%

H-Pro-OtBu Structure

2812-46-6

H-Pro-OtBu

Fmoc-Pro-OH Structure

71989-31-6

Fmoc-Pro-OH

~%

H-Pro-OtBu Structure

2812-46-6

H-Pro-OtBu


Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved