Action of serine carboxypeptidases on endopeptidase substrates, N-acyldipeptideamides

…, K Tanabe, K Yamashita, M Fukuda

Index: Kunugi, Shigeru; Tanabe, Kazuo; Yamashita, Kouji; Fukuda, Mitsuhiro Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 4 p. 1399 - 1402

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Citation Number: 8

Abstract

Action patterns of two serine carboxypeptidases, one from yeast (Y) and the other from wheat bran (W), on N-[3-(2-furyl) acryloyl]-(Fua-) dipeptideamide substrates were examined by HPLC and amino acid analysis. In the reaction of the wheat enzyme the substrates were hydrolyzed to Fua-amino acid and no sufficient amount of Fua-dipeptides were detected on HPLC in the product mixtures. Very few or no free amino acids were observed by amino ...