FA-Phe-Phe-OH

Modify Date: 2024-01-09 20:51:08

FA-Phe-Phe-OH structure	Common Name	FA-Phe-Phe-OH
	CAS Number	83661-95-4	Molecular Weight	432.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₄N₂O₅	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of FA-Phe-Phe-OH

FA-Phe-Phe is a furylacryloyl (fa)-amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE). FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].

Name	N-[(2E)-3-(2-Furyl)-2-propenoyl]-L-phenylalanyl-L-phenylalanine
Synonym	More Synonyms

Description	FA-Phe-Phe is a furylacryloyl (fa)-amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE). FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
References	[1]. Mayer M, et al. Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy. J Med Chem. 2000 Jun 1;43(11):2093-9. [2]. Ostrowska H, et al. Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme. Biochem Biophys Res Commun. 1997 May 29;234(3):729-32.

Description

FA-Phe-Phe is a furylacryloyl (fa)-amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE). FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)

References

[1]. Mayer M, et al. Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy. J Med Chem. 2000 Jun 1;43(11):2093-9.

[2]. Ostrowska H, et al. Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme. Biochem Biophys Res Commun. 1997 May 29;234(3):729-32.

Molecular Formula	C₂₅H₂₄N₂O₅
Molecular Weight	432.47
Exact Mass	432.16900
PSA	115.62000
LogP	4.51300
Storage condition	-20°C

FA-Phe-Phe-OH MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3

L-Phenylalanine

CAS#:63-91-2

2,5-dioxopyrrol...

CAS#:71067-15-7

FA-Phe-Phe-OH

CAS#:83661-95-4

Literature: Tanco, Sebastian; Zhang, Xin; Morano, Cain; Aviles, Francesc Xavier; Lorenzo, Julia; Fricker, Lloyd D. Journal of Biological Chemistry, 2010 , vol. 285, # 24 p. 18385 - 18396

N-[3-(2-furyl)a...

CAS#:26390-02-3

~56%

fa-phe-oh

CAS#:71115-83-8

FA-Phe-Phe-OH

CAS#:83661-95-4

Literature: Kunugi, Shigeru; Tanabe, Kazuo; Yamashita, Kouji; Fukuda, Mitsuhiro Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 4 p. 1399 - 1402

fa-phe-oh

CAS#:71115-83-8

FA-Phe-Phe-OH

CAS#:83661-95-4

Literature: Tanco, Sebastian; Zhang, Xin; Morano, Cain; Aviles, Francesc Xavier; Lorenzo, Julia; Fricker, Lloyd D. Journal of Biological Chemistry, 2010 , vol. 285, # 24 p. 18385 - 18396

Precursor 3
CAS#:63-91-2 L-Phenylalanine CAS#:26390-02-3 N-[3-(2-furyl)a... CAS#:71115-83-8 fa-phe-oh
DownStream 0

A unique activity assay for carboxypeptidase A in human serum.

Anal. Biochem. 125 , 420, (1982)

N-(3-(2-furyl)acryloyl)phenylalanine

3-(2-FURYL)ACRYLOYL-L-PHENYLALANINE

3-(2-furyl)acryloylglycyl-L-phenylalanine-L-phenylalanine

N-<3-(2-furyl)acryloyl>-Phe-Phe

FA-PHENYLALANINE

Fua-Phe-Phe-OH

N-<3-(2-furyl)acryloyl>-Phe

Fua-Phe-Phe

N-[3-(2-FURYL)ACRYLOYL]-L-PHENYLALANINE

N-<3-<2>Furyl-acryloyl>-L-phenylalanin

FA-Phe-Phe-OH

FA-Phe-Phe-OH

Use of FA-Phe-Phe-OH

Names

FA-Phe-Phe-OH Biological Activity

Chemical & Physical Properties

MSDS

Safety Information

Synthetic Route

Precursor & DownStream

Articles1

Synonyms