Synlett

Regioselective Alkylation of Catechols via Mitsunobu Reactions

X Wang, T Ju, X Li, X Cao

Index: Wang, Xiaolong; Ju, Tingting; Li, Xiaodong; Cao, Xiaoping Synlett, 2010 , # 19 p. 2947 - 2949

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Citation Number: 6

Abstract

Abstract A mild and efficient Mitsunobu protocol for the regioselective alkylation of catechols such as 3, 4-dihydroxybenzaldehyde and methyl 3, 4-dihydroxybenzoate is described. The para-alkylation products could be easily prepared via the Mitsunobu reaction with high selectivity in moderate to good yields.