Convenient Synthesis of 1-Oxa-3, 8-diazaspiro [4, 5] Decan-2-ones

R Somanathan, IA Rivero, GI Nuñez…

Index: Somanathan; Rivero; Nunez; Hellberg Synthetic Communications, 1994 , vol. 24, # 10 p. 1483 - 1487

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Citation Number: 11

Abstract

R. Somanathan*, LA. Rivero, GI Nuiiez and LH Hellberg. ... Centro de Graduados del lnstituto Tecnologico de Tijuana. Apdo Postal 1166, Tijuana BC MEXICO. ... ABSTRACT: Synthesis of 1 -oxa-3,8-diazospiro [4,5] decan-2- ones from 4-pyridone by addition of trimethylsilyl cyanide. ... Continuing our interest in the synthesis of new antihypertensive agents (l), the syntheses of 9-substituted-1 - oxa -3,8-diazaspiro [4,5]- decan-2-ones reported by Clark and co- ...