Tetrahedron

Facile synthesis of aryl (het) cyclopropane catalyzed by palladacycle

M Zhang, X Cui, X Chen, L Wang, J Li, Y Wu, L Hou…

Index: Zhang, Min; Cui, Xiuling; Chen, Xiaopei; Wang, Lianhui; Li, Jingya; Wu, Yusheng; Hou, Lifen; Wu, Yangjie Tetrahedron, 2012 , vol. 68, # 3 p. 900 - 905

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Citation Number: 14

Abstract

Sphos (2-dicyclohexylphosphino-2′, 6′-dimethoxy-1, 1′-biphenyl) adduct of cyclopalladated ferrocenylimine (IIe) exhibited highly catalytic activity for the Suzuki cross- coupling reaction of cyclopropylboronic acid with aryl (het) halides with 1mol% catalyst loading. This process was applied to both of aryl and heteroaryl halides (Br and Cl), and made the various arylcyclopropane and heteroarylcyclopropane to be easily synthesized. ...