e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Tetrahedron

Generation of aminyl radicals using sulfenamides as synthetic precursors

WR Bowman, DN Clark, RJ Marmon

Index: Bowman, W. Russell; Clark, David N.; Marmon, Robert J. Tetrahedron, 1994 , vol. 50, # 4 p. 1275 - 1294

Full Text: HTML

Citation Number: 65

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Sulfenamides are synthesised from reaction between amines and N-(benzenesulfenyl)-phthalimide or benzenesulfenyl chloride. The sulfenamides undergo reaction with tributyltin hydride to yield aminyl radicals which can be cyclised onto suitable alkenes.

N-(4-methylbenzylidene)cyclopropanamine Structure

N-(4-methylbenz...

~%

CYCLOPROPYL-(4-METHYL-BENZYL)-AMINE Structure

CYCLOPROPYL-(4-...

p-Tolualdehyde Structure

~%

CYCLOPROPYL-(4-METHYL-BENZYL)-AMINE Structure

CYCLOPROPYL-(4-...

p-Tolualdehyde Structure

~%

N-[(4-methylphenyl)methyl]-N-phenylsulfanylcyclobutanamine Structure

N-[(4-methylphe...

Thiophenol Structure

~%

N-[(4-methylphenyl)methyl]-N-phenylsulfanylcyclobutanamine Structure

N-[(4-methylphe...

N-[(4-Methylphenyl)methylene]cyclobutanamine Structure

N-[(4-Methylphe...

~%

N-[(4-methylphenyl)methyl]-N-phenylsulfanylcyclobutanamine Structure

N-[(4-methylphe...

(Chlorosulfanyl)benzene Structure

(Chlorosulfanyl...

~%

N-[(4-methylphenyl)methyl]-N-phenylsulfanylcyclobutanamine Structure

N-[(4-methylphe...

1-cyclohexyl-3-phenyl-1-propyl phenyl sulfide Structure

1-cyclohexyl-3-...

~29%

N/A Structure

phenylthiotri-n-butyltin Structure

phenylthiotri-n...

n-butylamine Structure

Cinnamyl bromide Structure

Cinnamyl bromide

~69%

N-[(E)-3-phenyl-2-propenyl]-n-butylamine Structure

N-[(E)-3-phenyl...

p-Tolualdehyde Structure

~%

N-(4-Methylbenzyl)-1-butanamine Structure

N-(4-Methylbenz...

N-[(4-Methylphenyl)methylene]cyclobutanamine Structure

N-[(4-Methylphe...

~%

N-(4-Methylbenzyl)-1-butanamine Structure

N-(4-Methylbenz...

4-Methylbenzyl bromide Structure

4-Methylbenzyl ...

n-butylamine Structure

~%

N-(4-Methylbenzyl)-1-butanamine Structure

N-(4-Methylbenz...

Triphenylphosphine Structure

Triphenylphosphine

4-Bromobutanenitrile Structure

4-Bromobutanenitrile

~81%

Phosphonium,(3-cyanopropyl)triphenyl-, bromide (1:1) Structure

Phosphonium,(3-...

CYCLOPROPYL-(4-METHYL-BENZYL)-AMINE Structure

CYCLOPROPYL-(4-...

~%

N-(4-Methylbenzyl)-1-propanamine Structure

N-(4-Methylbenz...

N/A Structure

~%

N-(4-Methylbenzyl)-1-propanamine Structure

N-(4-Methylbenz...

p-Tolualdehyde Structure

~%

N-(4-Methylbenzyl)-1-propanamine Structure

N-(4-Methylbenz...

N-(4-methylbenzylidene)cyclopropanamine Structure

N-(4-methylbenz...

~%

N-(4-Methylbenzyl)-1-propanamine Structure

N-(4-Methylbenz...

Propylamine Structure

4-Methylbenzyl bromide Structure

4-Methylbenzyl ...

~%

N-(4-Methylbenzyl)-1-propanamine Structure

N-(4-Methylbenz...

N-cyclopentyl-1-(p-tolyl)methanimine Structure

N-cyclopentyl-1...

~%

N-[(4-methylphenyl)methyl]cyclopentanamine,hydrochloride Structure

N-[(4-methylphe...

p-Tolualdehyde Structure

~%

N-[(4-methylphenyl)methyl]cyclopentanamine,hydrochloride Structure

N-[(4-methylphe...

Cyclopentylamine Structure

Cyclopentylamine

~%

N-[(4-methylphenyl)methyl]cyclopentanamine,hydrochloride Structure

N-[(4-methylphe...