Synthetic Communications

Solvent??Free, Palladium??Catalyzed Suzuki–Miyaura Cross??Couplings of Aryl Chlorides with Arylboronic Acids

JH Li, CL Deng, YX Xie

Index: Li, Jin-Heng; Deng, Chen-Liang; Xie, Ye-Xiang Synthetic Communications, 2007 , vol. 37, # 14 p. 2433 - 2448

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Citation Number: 20

Abstract

Abstract Pd (MeCN) 2Cl2/PCy3 was found to be an efficient catalytic system for the Suzuki– Miyaura cross??couplings of aryl chlorides with arylboronic acids under solvent??free conditions. Furthermore, the presence of the conventional solvents had deleterious effect on the reaction. In the presence of Pd (MeCN) 2Cl2, PCy3, and TBAF (tetra??n??butylammonium fluoride), a number of aryl chlorides including heteroaryl chlorides were coupled with ...

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