Enantioselective Baeyer–Villiger Oxidation Catalyzed by Palladium (II) Complexes with Chiral P, N-Ligands∥

…, M Bell, ME Swarbrick, P Kočovský

Index: Malkov, Andrei V.; Friscourt, Frederic; Bell, Mark; Swarbrick, Martin E.; Kocovsky, Pavel Journal of Organic Chemistry, 2008 , vol. 73, # 11 p. 3996 - 4003

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Citation Number: 55

Abstract

Asymmetric Baeyer–Villiger reaction of symmetrical cyclobutanones 1a− j with urea− hydrogen peroxide (UHP) can be catalyzed by a complex of Pd (II) and the new terpene- derived P, N-ligand 7. The resulting lactones 2a− j were obtained in high yields and with good enantioselectivity (≤ 81% ee).