Organic letters

In (III)-mediated chemoselective dehydrogenative interaction of ClMe2SiH with carboxylic acids: Direct chemo-and regioselective Friedel-Crafts acylation of aromatic …

SA Babu, M Yasuda, A Baba

Index: Babu, Srinivasarao Arulananda; Yasuda, Makoto; Baba, Akio Organic Letters, 2007 , vol. 9, # 3 p. 405 - 408

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Citation Number: 32

Abstract

Chemoselective dehydrogenative interaction of ClMe2SiH with a carboxylic acid group in the presence of InX3 is reported. 13C NMR investigation revealed the formation of PhCOOSi (Cl) Me2 as the major transient intermediate. Chemo-and regioselective Friedel-Crafts acylation of aromatic ethers directly from carboxylic acids was established.