Synthesis and crystallographic analysis of short pyridine-based oligoamides as DNA-targeting supramolecular binders

DO Frimannsson, T McCabe, W Schmitt…

Index: Frimannsson, Daniel O.; McCabe, Thomas; Schmitt, Wolfgang; Lawler, Mark; Gunnlaugsson, Thorfinnur Supramolecular Chemistry, 2010 , vol. 22, # 9 p. 483 - 490

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Citation Number: 3

Abstract

In this study, the synthesis of the pyridine peptides 1–4, formed from amino-picolinic acid, and pyridine peptide 5, made from coupling of a mono-protected pyridine diamine to a mono- protected pyridine dicarboxylic acid and the X-ray crystallographic structures of 1 and 5 are discussed, along with their supramolecular interactions in the solid state. The structure of these compounds showed that they possess concave appearance which can be ...