Chemistry–A European Journal

Copper??Catalyzed Aerobic Oxidative C H and C C Functionalization of 1??[2??(Arylamino) aryl] ethanones Leading to Acridone Derivatives

J Yu, H Yang, Y Jiang, H Fu

Index: Yu, Jipan; Yang, Haijun; Jiang, Yuyang; Fu, Hua Chemistry - A European Journal, 2013 , vol. 19, # 13 p. 4271 - 4277

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Citation Number: 2

Abstract

Abstract Efficient copper-catalyzed aerobic oxidative C [BOND] H and C [BOND] C functionalization of 1-[2-(arylamino) aryl] ethanones leading to acridones has been developed. The procedure involves cleavage of aromatic C [BOND] H and acetyl C [BOND] C bonds with intramolecular formation of a diarylketone bond. The protocol uses inexpensive Cu (O 2 CCF 3) 2 as catalyst, pyridine as additive, and economical and ...