Acridine

Modify Date: 2026-07-01 13:24:34

Acridine Structure
Acridine structure
Common Name Acridine
CAS Number 260-94-6 Molecular Weight 179.217
Density 1.2±0.1 g/cm3 Boiling Point 346.7±11.0 °C at 760 mmHg
Molecular Formula C13H9N Melting Point 106-109 °C
MSDS Chinese USA Flash Point 153.8±11.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name acridine
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.2±0.1 g/cm3
Boiling Point 346.7±11.0 °C at 760 mmHg
Melting Point 106-109 °C
Molecular Formula C13H9N
Molecular Weight 179.217
Flash Point 153.8±11.9 °C
Exact Mass 179.073502
PSA 12.89000
LogP 3.40
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.727
InChIKey DZBUGLKDJFMEHC-UHFFFAOYSA-N
SMILES c1ccc2nc3ccccc3cc2c1
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility dioxane: 0.1 g/mL, clear

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR7175000
CHEMICAL NAME :
Acridine
CAS REGISTRY NUMBER :
260-94-6
BEILSTEIN REFERENCE NO. :
0120200
LAST UPDATED :
199710
DATA ITEMS CITED :
18
MOLECULAR FORMULA :
C13-H9-N
MOLECULAR WEIGHT :
179.23
WISWESSER LINE NOTATION :
T C666 BNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - necrotic changes Blood - changes in erythrocyte (RBC) count
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Behavioral - excitement
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4500 mg/kg/45D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Blood - pigmented or nucleated red blood cells Blood - changes in other cell count (unspecified)

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Bird - chicken Leukocyte
DOSE/DURATION :
100 umol/L
REFERENCE :
JMOBAK Journal of Molecular Biology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,18,1961 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Gen Indu):8H TWA 0.2 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.2 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.2 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.2 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 03490 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 34 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 03490 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 70 (estimated)

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S22-S36
RIDADR UN 2713 6.1/PG 3
WGK Germany 3
RTECS AR7175000
Packaging Group III
Hazard Class 6.1
HS Code 2933990090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles16

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

In vitro toxicological assessment of iron oxide, aluminium oxide and copper nanoparticles in prokaryotic and eukaryotic cell types.

Drug Chem. Toxicol. 38 , 152-61, (2015)

Metallic nanoparticles (NPs) have a variety of applications in different industries including pharmaceutical industry where these NPs are used mainly for image analysis and drug delivery. The increasi...

By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy.

Oncotarget 6(4) , 2315-30, (2015)

Basal-like breast cancer is an aggressive tumor subtype with a poor response to conventional therapies. Tumor formation and relapse are sustained by a cell subset of Breast Cancer Stem Cells (BrCSCs)....

The ionization mechanisms in direct and dopant-assisted atmospheric pressure photoionization and atmospheric pressure laser ionization.

J. Am. Soc. Mass Spectrom. 25(11) , 1870-81, (2014)

A novel, gas-tight API interface for gas chromatography-mass spectrometry was used to study the ionization mechanism in direct and dopant-assisted atmospheric pressure photoionization (APPI) and atmos...

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Acrydine
Acridine
EINECS 205-971-6
dibenzo[b,e]pyridine
2,3-Benzoquinoline
benzoquinolinylidene
10-azaanthracene
Akridin
9-Azaanthracene
2,3,5,6-Dibenzopyridine
MFCD00005025

 Acridine | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the English name of acridine?
A: The English name of acridine is acridine.
Q: What is the boiling point of acridine?
A: Boiling point of acridine is 346.7±11.0 °C at 760 mmHg.
Q: What is the LogP of acridine?
A: LogP of acridine is 3.40.
Q: What is the CAS number of acridine?
A: CAS number of acridine is 260-94-6.
Q: What is the melting point of acridine?
A: Melting point of acridine is 106-109 °C.
Q: How is the water solubility of acridine?
A: Water solubility of acridine: dioxane: 0.1 g/mL, clear.
Q: What is the InChIKey of acridine?
A: InChIKey of acridine is DZBUGLKDJFMEHC-UHFFFAOYSA-N.
Q: What English synonyms does acridine have?
A: English synonyms of acridine: Acrydine, Acridine, EINECS 205-971-6, dibenzo[b,e]pyridine, 2,3-Benzoquinoline, benzoquinolinylidene, 10-azaanthracene, Akridin, 9-Azaanthracene, 2,3,5,6-Dibenzopyridine, MFCD00005025.
Q: What are the upstream materials of acridine?
A: Related upstream materials(CAS) of acridine: 10399-73-2;247924-02-3;538-51-2;622-37-7;100-52-7;28059-64-5;578-95-0;5336-90-3.
Q: What is the safety information for acridine?
A: Safety information for acridine: S22-S36.

 Acridinefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
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