The Journal of Organic Chemistry

One-pot synthesis of phosphonic acid diesters

A Munoz, C Hubert, JL Luche

Index: Munoz, Aurelio; Hubert, Cathy; Luche, Jean-Louis Journal of Organic Chemistry, 1996 , vol. 61, # 17 p. 6015 - 6017

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Citation Number: 20

Abstract

Phosphonic acid diesters are useful intermediates in chemistry, 1 and finding new synthetic routes to these compounds constitutes a valuable target. Known preparations include transesterification of easily available members of the family, 2 acidolyses or hydrolyses of phosphorochloridites or mixed anhydrides, 3-5 addition of phosphonic acid to oxiranes, 6 or alcoholysis of bis (N, N-dimethylamino) phosphonate. 7 Among these, the hydrolysis of ...