Nickel??Catalyzed Cyclization of ortho??Iodoketoximes and ortho??Iodoketimines with Alkynes: Synthesis of Highly Substituted Isoquinolines and Isoquinolinium Salts

WC Shih, CC Teng, K Parthasarathy…

Index: Shih, Wei-Chun; Teng, Chu-Chun; Parthasarathy, Kanniyappan; Cheng, Chien-Hong Chemistry - An Asian Journal, 2012 , vol. 7, # 2 p. 306 - 313

Full Text: HTML

Citation Number: 24

Abstract

Abstract A convenient method for the synthesis of highly substituted isoquinolines and isoquinolinium salts by the nickel-catalyzed cyclization of ortho-haloketoximes and- ketimines, respectively, with alkynes is described. The reaction of ortho-haloketoximes ...