e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Regioselective side-chain nitration of polymethylbenzenes directed by an acyl function and its application to the synthesis of polysubstituted phthalic acid derivatives
…, K Teramoto, H Takahashi, H Yamamoto…
Index: Keumi, Takashi; Morita, Toshio; Teramoto, Koichi; Takahashi, Hisakazu; Yamamoto, Hiroshi; et al. Journal of Organic Chemistry, 1986 , vol. 51, # 18 p. 3439 - 3446
Nitration of three types of tetramethylacetophenones and pentamethylacetophenone with fuming nitric acid in acetic anhydride was carried out. The product distributions were compared with those estimated from substituent effects. A variety of acylpentainethylbenzenes including pentamethylbenzoic acid were reacted with the nitrating system to give regioselectively 2-(nitromethyl)-3, 4, 5, 6-tetramethylacylbenzenes. ...
