Tetrahedron Letters

A facile synthesis of 2, 3-disubstituted furo [2, 3-b] pyridines

GL Beutner, JT Kuethe, N Yasuda

Index: Beutner, Gregory L.; Kuethe, Jeffrey T.; Yasuda, Nobuyoshi Tetrahedron Letters, 2009 , vol. 50, # 7 p. 781 - 784

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Citation Number: 3

Abstract

In a three-step sequence starting from readily available starting materials, 2, 3-carbon disubstituted furo [2, 3-b] pyridines can be accessed in good yields and purity. Furo [2, 3-b] pyridines bearing ester, amide and ketone groups at the 2-position can be prepared with a variety of aryl and alkyl groups at the 3-position.