N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide

Modify Date: 2024-01-02 14:34:45

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide Structure
N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide structure
Common Name N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide
CAS Number 116332-61-7 Molecular Weight 233.187
Density 1.3±0.1 g/cm3 Boiling Point 305.7±42.0 °C at 760 mmHg
Molecular Formula C10H10F3NO2 Melting Point N/A
MSDS N/A Flash Point 138.7±27.9 °C

 Names

Name N-methoxy-N-methyl-4-(trifluoromethyl)benzamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 305.7±42.0 °C at 760 mmHg
Molecular Formula C10H10F3NO2
Molecular Weight 233.187
Flash Point 138.7±27.9 °C
Exact Mass 233.066360
PSA 29.54000
LogP 2.41
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.468

 Synthetic Route

~99%

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide Structure

N-Methoxy-N-met...

CAS#:116332-61-7

Literature: Gomtsyan, Arthur; Bayburt, Erol K.; Keddy, Ryan; Turner, Sean C.; Jinkerson, Tammie K.; Didomenico, Stanley; Perner, Richard J.; Koenig, John R.; Drizin, Irene; McDonald, Heath A.; Surowy, Carol S.; Honore, Prisca; Mikusa, Joe; Marsh, Kennan C.; Wetter, Jill M.; Faltynek, Connie R.; Lee, Chih-Hung Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 14 p. 3894 - 3899

~90%

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide Structure

N-Methoxy-N-met...

CAS#:116332-61-7

Literature: Niu, Teng; Zhang, Weiming; Huang, Danfeng; Xu, Changming; Wang, Haifeng; Hu, Yulai Organic Letters, 2009 , vol. 11, # 19 p. 4474 - 4477

~35%

Detail
Literature: Wieckowska, Anna; Fransson, Rebecca; Odell, Luke R.; Larhed, Mats Journal of Organic Chemistry, 2011 , vol. 76, # 3 p. 978 - 981

~39%

Detail
Literature: Wieckowska, Anna; Fransson, Rebecca; Odell, Luke R.; Larhed, Mats Journal of Organic Chemistry, 2011 , vol. 76, # 3 p. 978 - 981

~%

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide Structure

N-Methoxy-N-met...

CAS#:116332-61-7

Literature: Journal of Medicinal Chemistry, , vol. 55, # 9 p. 4189 - 4204

~99%

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide Structure

N-Methoxy-N-met...

CAS#:116332-61-7

Literature: Dainippon Sumitomo Pharma Co., Ltd. Patent: EP1647546 A1, 2006 ; Location in patent: Page/Page column 34 ;

~%

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide Structure

N-Methoxy-N-met...

CAS#:116332-61-7

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 18 p. 5567 - 5571

 Synonyms

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide
N-methyl-N-(methyloxy)-4-(trifluoromethyl)benzamide
4-(trifluoromethyl)-N-methoxy-Nmethylbenzamide
N-methoxy-N-methyl-4-trifluoromethylbenzamide
Benzamide, N-methoxy-N-methyl-4-(trifluoromethyl)-