An efficient and facile procedure for the synthesis of 4, 6??diaryl??2 (1H)??pyridones under solvent??free conditions

L Rong, H Wang, J Shi, F Yang, H Yao…

Index: Rong, Liangce; Wang, Haiying; Shi, Jingwen; Yang, Fang; Yao, Hao; Tu, Shuajiang; Shi, Daqing Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 6 p. 1505 - 1508

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Citation Number: 13

Abstract

The nucleus of 2-pyridone occurs widely in the structures of biologically natural alkaloids [1]. Many derivatives of 2-pyridone are frequently used as intermediates for the construction of alkaloids [2]. Even some derivatives of 4, 6-diaryl-2-pyridone, such as the simple structural related 2-pyridones, are recognized as potent LTB4 antagonist [3]. Numerous methods [4] have been reported for the synthesis of 2-pyridone derivatives, because of the biological ...