Palladium??Catalyzed Regioselective C–H Bond ortho??Acetoxylation of Arylpyrimidines

X Zheng, B Song, B Xu

Index: Zheng, Xiaojian; Song, Bingrui; Xu, Bin European Journal of Organic Chemistry, 2010 , # 23 p. 4376 - 4380

Full Text: HTML

Citation Number: 32

Abstract

Abstract An efficient and regioselective palladium-catalyzed orthoC–H acetoxylation reaction was developed to afford ortho monoacetoxylated arylpyrimidines in good to excellent yields by using cupric trifluoroacetate as a cocatalyst. A wide variety of oxygenated arylpyrimidines were prepared with high regioselectivity and functional group tolerance.