Solvent system ethanol-2, 2, 2-trifluoroethanol as a medium for solvolytic displacement

DA Da Roza, LJ Andrews…

Index: da Roza,D.A. et al. Journal of the American Chemical Society, 1973 , vol. 95, p. 7003 - 7009

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Citation Number: 22

Abstract

Abstract: A comparative rate study of the solvolyses of benzyl bromide and chloride and their m-fluoro and p-methyl derivatives in various mixtures of ethanol and 2, 2, 2-trifluoroethanol has been conducted. The reactivity of p-methylbenzyl chloride increases and that of m- fluorobenzyl chloride decreases with increasing trifluoroethanol content of the medium; benzyl chloride is relatively insensitive to changes in solvent composition. These reactivity ...