Auto??Tandem Catalysis: Synthesis of Acridines by Pd??Catalyzed C= C Bond Formation and C (sp2)–N Cross??Coupling

…, Y Yang, Q Xiao, Y Zhang, J Wang

Index: Huang, Zhongxing; Yang, Yang; Xiao, Qing; Zhang, Yan; Wang, Jianbo European Journal of Organic Chemistry, 2012 , # 33 p. 6586 - 6593

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Citation Number: 15

Abstract

Abstract A facile palladium-catalyzed synthesis of acridines has been realized by consecutive C= C double bond formation and C–N cross-coupling. A variety of functionalized acridines can be accessed from easily available o-dihalobenzenes and N- tosylhydrazones in a single operation. This one-pot protocol has a wide scope with respect to both coupling partners, and provides an efficient route to functionalized acridine ...