Synthesis of 6-cyano-2, 2-dimethyl-2H-1-benzopyran and other substituted 2, 2-dimethyl-2H-1-benzopyrans

JT North, DR Kronenthal, AJ Pullockaran…

Index: North, Jeffrey T.; Kronenthal, David R.; Pullockaran, Annie J.; Real, Sharon D.; Chen, Helen Y. Journal of Organic Chemistry, 1995 , vol. 60, # 11 p. 3397 - 3400

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Citation Number: 53

Abstract

In recent years there has been increased interest in the synthesis of 2H-1-benzopyrans (chromenes) due to the number of compounds which possess this subgroup and show antidepressant, antihypertensive, and hypoglycemic activity as well as other biological effects. lB2 The literature contains a variety of synthetic approaches to the chromene ring structure, much of which has been compiled into comprehensive review^.^ As part of an ...