A Highly Practical and Reliable Nickel Catalyst for Suzuki–Miyaura Coupling of Aryl Halides

YL Zhao, Y Li, SM Li, YG Zhou, FY Sun…

Index: Zhao, Yu-Long; Li, You; Li, Shui-Ming; Zhou, Yi-Guo; Sun, Feng-Yi; Gao, Lian-Xun; Han, Fu-She Advanced Synthesis and Catalysis, 2011 , vol. 353, # 9 p. 1543 - 1550

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Citation Number: 32

Abstract

Abstract We disclose that [1, 3-bis (diphenylphosphino) methane] nickel (II) chloride [NiCl 2 (dppp)] is a highly active, universally applicable, cheap, and stable catalyst for Suzuki– Miyaura cross-coupling reactions of aryl halides with a catalyst loading of lower than 1 mol%, and more notably, in the absence of extra supporting ligands. Under the optimized reaction conditions, a broad range of aryl bromides as well as the notoriously unreactive ...