Molecular Nutrition & Food Research 2018-04-14

Flaxseed Oil Attenuates Intestinal Damage and Inflammation by Regulating Necroptosis and TLR4/NOD Signaling Pathways Following Lipopolysaccharide Challenge in a Piglet Model

Huiling Zhu; Haibo Wang; Shuhui Wang; Zhixiao Tu; Lin Zhang; Xiuying Wang; Yongqing Hou; Chunwei Wang; Jie Chen; Yulan Liu

Index: 10.1002/mnfr.201700814

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Abstract

Flaxseed oil is a rich source of α‐linolenic acid (ALA), which is the precursor of the long‐chain n‐3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). This study investigates the protective effect of flaxseed oil against intestinal injury induced by lipopolysaccharide (LPS).