Molecular Catalysis 2018-03-20

Mechanistic aspects of copper (II)-catalyzed synthesis of sulfones from sulfinate salts and aryl halides under C-S coupling

Xin Ge, Fengli Sun, Xuemin Liu, Xinzhi Chen, Chao Qian, Shaodong Zhou

Index: 10.1016/j.mcat.2017.12.016

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Abstract

Copper(II)-catalyzed synthesis of sulfones from sulfinate salts and aryl halides was investigated by means of a combination of experiment and DFT calculation. Experimental results demonstrated the wide applicability of the title approach. The reaction mechanisms are revealed by in-situ IR and theoretical study. It reveals remarkable ligand effect the bidentate amine plays in the reaction, that is, it initially activats the C-I bond of iodobenzene so as to enhance the whole catalytic process.