e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

A convenient synthesis of (2??styrylchromon??8??yl) acetic acids

F Zammattio, JD Brion, L Belachmi…

Index: Zammattio, F.; Brion, J. D.; Belachmi, L.; Le Baut, G. Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 8 p. 2013 - 2019

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Citation Number: 7

Abstract

December 1991 A Convenient Synthesis of (2-Styrylchromon- 8-yl)acetic Acids F. Zammattio, JD Brion [1]*, L. Belachmi and G. Le Baut Laboratoire de Chimie Thérapeutique, UFR des Sciences Pharmaceutiques, 1 rue Gaston Veil, F-44035 Nantes Cedex, France Received March 12, 1991 (2-Styrylchromon-8-yl)acetic acids, structural analogs of (flavon-8-yl)acetic acid (FAA) have been synthe- sized with satisfactory yields according to two different methods. ...

Formaldehyde Structure

7-methoxy-2-methyl-4H-chromen-4-one Structure

7-methoxy-2-met...

~34%

8-(chloromethyl)-7-methoxy-2-methylchromen-4-one Structure

8-(chloromethyl...

3,8-bis(chloromethyl)-7-methoxy-2-methylchromen-4-one Structure

3,8-bis(chlorom...

Paeonol Structure

~%

8-(chloromethyl)-7-methoxy-2-methylchromen-4-one Structure

8-(chloromethyl...

2,8-dimethylchromone Structure

2,8-dimethylchromone

~%

2-(2-methyl-4-oxochromen-8-yl)acetonitrile Structure

2-(2-methyl-4-o...

methyl 2-hydroxy-3-methylbenzoate Structure

methyl 2-hydrox...

~%

2-(2-methyl-4-oxochromen-8-yl)acetonitrile Structure

2-(2-methyl-4-o...

(1-(2-hydroxy-3-methylbenzoyl)methylene)triphenylphosphorane Structure

(1-(2-hydroxy-3...

~%

2-(2-methyl-4-oxochromen-8-yl)acetonitrile Structure

2-(2-methyl-4-o...

Formaldehyde Structure

7-methoxy-2-methyl-4H-chromen-4-one Structure

7-methoxy-2-met...

~61%

8-(chloromethyl)-7-methoxy-2-methylchromen-4-one Structure

8-(chloromethyl...

3,8-bis(chloromethyl)-7-methoxy-2-methylchromen-4-one Structure

3,8-bis(chlorom...

Paeonol Structure

~%

3,8-bis(chloromethyl)-7-methoxy-2-methylchromen-4-one Structure

3,8-bis(chlorom...

2-(2-methyl-4-oxochromen-8-yl)acetonitrile Structure

2-(2-methyl-4-o...

~95%

2-(2-methyl-4-oxo-chromen-8-yl)acetic acid Structure

2-(2-methyl-4-o...

2,8-dimethylchromone Structure

2,8-dimethylchromone

~%

2-(2-methyl-4-oxo-chromen-8-yl)acetic acid Structure

2-(2-methyl-4-o...

methyl 2-hydroxy-3-methylbenzoate Structure

methyl 2-hydrox...

~%

2-(2-methyl-4-oxo-chromen-8-yl)acetic acid Structure

2-(2-methyl-4-o...

(1-(2-hydroxy-3-methylbenzoyl)methylene)triphenylphosphorane Structure

(1-(2-hydroxy-3...

~%

2-(2-methyl-4-oxo-chromen-8-yl)acetic acid Structure

2-(2-methyl-4-o...

Formaldehyde Structure

7-methoxy-2,3-dimethyl-chromen-4-one Structure

7-methoxy-2,3-d...

~89%

8-(chloromethyl)-7-methoxy-2,3-dimethylchromen-4-one Structure

8-(chloromethyl...

2'-Hydroxy-4'-methoxypropiophenone Structure

2'-Hydroxy-4'-m...

~%

8-(chloromethyl)-7-methoxy-2,3-dimethylchromen-4-one Structure

8-(chloromethyl...

2,8-dimethylchromone Structure

2,8-dimethylchromone

~80%

8-(bromomethyl)-2-methylchromen-4-one Structure

8-(bromomethyl)...

methyl 2-hydroxy-3-methylbenzoate Structure

methyl 2-hydrox...

~%

8-(bromomethyl)-2-methylchromen-4-one Structure

8-(bromomethyl)...

(1-(2-hydroxy-3-methylbenzoyl)methylene)triphenylphosphorane Structure

(1-(2-hydroxy-3...

~%

8-(bromomethyl)-2-methylchromen-4-one Structure

8-(bromomethyl)...