Pd??and Ni??Catalyzed Cross??Coupling Reactions of Functionalized Organozinc Reagents with Unsaturated Thioethers

L Melzig, A Metzger, P Knochel

Index: Melzig, Laurin; Metzger, Albrecht; Knochel, Paul Chemistry - A European Journal, 2011 , vol. 17, # 10 p. 2948 - 2956

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Citation Number: 60

Abstract

Abstract A variety of unsaturated thioethers have been subjected to cross-coupling reactions with functionalized zinc reagents in the presence of a transition-metal catalyst. Three different catalytic systems based on Pd (OAc) 2 or [Ni (acac) 2] and the ligands S-Phos or DPE-Phos gave the best results. N-Heterocyclic thioethers based on a pyridine, pyrimidine, pyrazine, pyridazine, triazine, benzothiazole, benzoxazole, pyrrole, or quinazoline ring, as ...