A series of isopropyl fatty esters having different chain length (C 13—C 23) were synthesized and formulated in lipid nanoparticles based on Precirol® ATO to evaluate their effect on the physicochemical properties of these latter. Moreover, drug loading and skin permeation of Econazole nitrate, chosen as a lipophilic model drug, were evaluated as well. The obtained nanosystems, prepared by high shear homogenization method, had a mean ...
