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Synthesis of Cell??Penetrating S??Galactosyl–Oligoarginine Peptides as Inducers of Recombinant Protein Expression under the Control of lac Operator/Repressor …

Y Mizuta, A Takasu, M Higuchi

Index: Mizuta, Yukina; Takasu, Akinori; Higuchi, Masahiro ChemPlusChem, 2013 , vol. 78, # 7 p. 677 - 683

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Abstract

Abstract The synthesis of glycodendrimers and glycopoly (oxazoline) s as inducers of recombinant protein expression has recently been reported; however, these compounds induced the expression of only small amounts of the green fluorescence protein (GFP), which was used as the model recombinant protein, because of their poor ability to penetrate the Escherichia coli cell membrane. Therefore, S-galactosyl–oligo (Arg) conjugates have ...