Cu–Mn Spinel Oxide Catalyzed Regioselective Halogenation of Phenols and N-Heteroarenes

…, PR Sharma, D Singh, RA Vishwakarma

Index: Singh, Parvinder Pal; Thatikonda, Thanusha; Kumar, K. A. Aravinda; Sawant, Sanghapal D.; Singh, Baldev; Sharma, Amit Kumar; Sharma; Singh, Deepika; Vishwakarma, Ram A. Journal of Organic Chemistry, 2012 , vol. 77, # 13 p. 5823 - 5828

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Citation Number: 14

Abstract

A novel simple, mild chemo-and regioselective method has been developed for the halogenation of phenols using Cu–Mn spinel oxide as a catalyst and N-halosuccinimide as halogenating agent. In the presence of Cu–Mn spinel oxide B, both electron-withdrawing and electron-donating groups bearing phenols gave monohalogenated products in good to excellent yields with highest para-selectivity. The para-substituted phenol gave ...