Synthetic communications

An efficient one-pot procedure for preparation of 2, 4 (1 H, 3 H)-quinazolinediones and 2-thioxoquinazolinone derivatives under microwave irradiation

J Azizian, AA Mohammadi, AR Karimi

Index: Azizian, Javad; Mohammadi, Ali A.; Karimi, Ali R. Synthetic Communications, 2003 , vol. 33, # 3 p. 415 - 420

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Citation Number: 40

Abstract

Abstract An efficient one-pot synthesis of 2, 4 (1 H, 3 H)-quinazolinediones and 2- thioxoquinazolinone derivatives are given by the condensation of isatoic anhydride, primary amine and urea or thiourea in the absence of organic or inorganic reagents under microwave irradiation.