Au/Ag-cocatalyzed aldoximes to amides rearrangement under solvent-and acid-free conditions

RS Ramón, J Bosson, S Díez-González…

Index: Ramon, Ruben S.; Bosson, Johann; Diez-Gonzalez, Silvia; Marion, Nicolas; Nolan, Steven P. Journal of Organic Chemistry, 2010 , vol. 75, # 4 p. 1197 - 1202

Full Text: HTML

Citation Number: 96

Abstract

The gold/silver-cocatalyzed conversion of aldoximes into primary amides is reported. The reaction, which proceeds under neat and acid-free conditions, allows for the conversion of a range of aldoximes, and is a rare example of cooperative catalysis involving well-defined gold species.

~98%

~24%

~92%

~91%

~47%

Synthesis, stability and in vitro dermal evaluation of amino...

[Mendes, Eduarda; Furtado, Tania; Neres, Joao; Iley, Jim; Jarvinen, Tomi; Rautio, Jarkko; Moreira, Rui Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 3 p. 809 - 816]

Photochemical cleavage and release of carboxylic acids from ...

[Ma, Chicheng; Steinmetz, Mark G.; Kopatz, Erica J.; Rathore, Rajendra Journal of Organic Chemistry, 2005 , vol. 70, # 11 p. 4431 - 4442]