Direct α??Alkylation of Ketones with Alcohols in Water

…, J Feng, Q Liu, Z Zhang, X Wang, X Zhang…

Index: Xu, Guoqiang; Li, Qiong; Feng, Jiange; Liu, Qiang; Zhang, Zuojun; Wang, Xicheng; Zhang, Xiaoyun; Mu, Xindong ChemSusChem, 2014 , vol. 7, # 1 p. 105 - 109

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Citation Number: 22

Abstract

Abstract The direct α-alkylation of ketones with alcohols has emerged as a new green protocol to construct C [BOND] C bonds with H 2 O as the sole byproduct. In this work, a very simple and convenient Pd/C catalytic system for the direct α-alkylation of ketones with primary alcohols in pure water is developed. Based on this catalytic system, aqueous mixtures of dilute acetone, 1-butanol, and ethanol (mimicking ABE fermentation products) ...