FEBS Journal

Benzimidazole analogs of l??tryptophan are substrates and inhibitors of tryptophan indole lyase from Escherichia coli

AP Harris, RS Phillips

Index: Harris, Austin P.; Phillips, Robert S. FEBS Journal, 2013 , vol. 280, # 8 p. 1807 - 1817

Full Text: HTML

Citation Number: 1

Abstract

Abstract Tryptophan indole lyase (TIL), an enzyme found in Escherichia coli and related enterobacteria, produces indole from l-tryptophan (l-Trp). Indole is a signaling molecule in bacteria, affecting biofilm formation, pathogenicity and antibiotic resistance. β-(Benzimidazol- 1-yl)-l-alanine (BZI-Ala), 2-amino-4-(benzimidazol-1-yl) butyric acid (homo-BZI-Ala) and 2- amino-5-(benzimidazol-1-yl) pentanoic acid (bishomo-BZI-Ala) were synthesized and ...

SCALABLE SYNTHESES OF N α-BENZYLOXYCARBONYL-l-ORNITHINE AND ...

[Masiukiewicz, Elzbieta; Wiejak, Stanislaw; Rzeszotarska, Barbara Organic Preparations and Procedures International, 2002 , vol. 34, # 5 p. 531 - 537]

NG-allyl-and NG-cyclopropyl-L-arginine: two novel inhibitors...

[Ferrario; Levi; Sala; Trupiano Synthetic Communications, 1991 , vol. 21, # 1 p. 99 - 105]

Über Peptidsynthesen, XXV. Synthese von Pro1??Arg2??, Ala4??...

[Schroeder,E. et al. Justus Liebigs Annalen der Chemie, 1964 , vol. 679, p. 221 - 231]