Synlett

Malononitrile as acylanion equivalent

S Förster, O Tverskoy, G Helmchen

Index: Foerster, Sebastian; Tverskoy, Olena; Helmchen, Guenter Synlett, 2008 , # 18 p. 2803 - 2806

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Citation Number: 21

Abstract

Abstract The oxidation of derivatives of malononitrile with peracid in methanol proceeds with loss of the cyano groups to yield methyl esters in high yield. The method was applied to a variety of malononitrile derivatives, some of which were prepared by Pd-or Ir-catalyzed asymmetric allylic substitution.