An efficient enantioselective preparation of 2-substituted-3-hydroxypropionic acids via chemo-enzymatic reaction

…, M Ohkubo, T Yonezawa, H Funabashi, J Hashimoto…

Index: Atsuumi, Shugo; Nakano, Masato; Koike, Yutaka; Tanaka, Seiichi; Ohkubo, Mitsuru; Yonezawa, Toshiko; Funabashi, Hiroshi; Hashimoto, Junko; Morishima, Hajime Tetrahedron Letters, 1990 , vol. 31, # 11 p. 1601 - 1604

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Citation Number: 28

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The key intermediates, 2-substituted-3-hydroxypropionic acids 1, of the potent renin inhibitors were synthesized enantioselectively starting from 2-substituted-l,3-propanediols via chemo-enzymatic reaction. ... The key intermediates, 2-substituted-3-hydroxypropionic acids 1, of the potent ...

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